The Best Non-clinical Service
GLP Certification Aurthority ChemOn Inc.
The Best Non-clinical Service
Enterprise placing human and life at the top ChemOn Inc.

Efficacy CRO

  • The best in vitro/in vivo models have been established in CORESTEMCHEMON to evaluate the efficacy of new drug candidates or raw materials for health functional foods, and we have extensive practical experience and provide customer-oriented and optimized evaluation services.
Efficacy evaluation C-arm µCT
Services
  • Cardiovascular disease
  • Thrombosis & Hemostasis
  • Urinary disease
  • Renal disease
  • Respiratory disease
  • CNS disease
  • Pain killing & Anti-inflammation
  • Arthritis & Immune disease
  • Gastrointestinal disease
  • Metabolic disease
  • Endocrinopathy
  • Dermatopathy
  • Anticancer
  • Anti bacteria
  • Liver disease
  • Biodistribution assessment
  • ETC
  • We have various in vitro and in vivo models and research experts for the evaluation of efficacy of new drug candidates, etc, and provide customer-oriented and optimized services.
Gene Analysis Center (Biodistribution Assessment Test)

  • For gene/cell therapeutic agents, quantitative PCR methods are performed to assess the in vivo distribution, engraftment, proliferation, and disappearance of cells for a sufficient period of time after administration of the test article.
    A quantitative of test article using real-time PCR to determine the route of administration, dosage, and clinical observation period for clinical trials by evaluating the in vivo disappearance time point after administration of biopharmaceuticals in animals.
ADME Center(Non-Clinical ADME evalution)

  • ADME is an abbreviation for absorption, distribution, metabolism, and excretion. It is a study that identifies the dynamics of drugs, such as efficacy and duration, mechanism of action, biodistribution, and concentration.
    Pharmacokinetics is a study that takes the ADME mechanism as a central research task, and is treated as very important in the stage just before conducting clinical trials in the process of developing new drugs (Pre-Clinical Trial: pre-clinical trial stage).
  • In vitro ADME
    • Microsomal stability assay
    • Plasma protein binding assay
    • Plasma stability
  • Rodent, non-rodent pharmacokinetics
    • Mouse, Rat, beagle, Guinea pig by various routes of administration
    • compared with IV infusion or bolus(plasma, urine, tissues)
    • Pharmacokinetic profile(phoenix WinNonlin)
  • Possessed equipment
    • LC-MS/MS:TQ-XS, 6495C
    • -ELISA system(ELISA:Enzyme-Linked immuno-Sorbent assay)
    • -SPE system (SPE: Solid-Phase Extraction)
효능팀 효능팀 효능팀 MD-CT(64channel) MD-CT(64channel) DR(X-ray) Optical imaging system UltraSound C-arm

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Head Quarter / Nonclinical Research Institute
  • 240, Nampyeongro, Yangji-myeon, Cheoin-gu, Yongin-si, Gyeonggi-do, 17162, Republic of Korea
  • Tel : +82-31-329-9900
  • Fax : +82-31-329-9902
  • E-mail : webmaster@csco.co.kr
  • Website : https://cro.corestemchemon.com
Gyeonggi Bio Research Center
  • 15F, Gyeonggi Bio Center, 147, Gwanggyo-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do, 16229, Republic of Korea
  • Tel : +82-31-888-6634
  • Fax : +82-31-888-6640
Chuncheon Bio Research Center
  • 2-8, BIO-3 32, Soyanggang-ro, Chuncheon-si, Gangwon-do, 24232, Republic of Korea
Corestemchemon US Inc.
  • 1952 Gallows Road Suite 110 Vienna, VA 22182